1) Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: Sensitivity analysis with glycosylation-
丂defective mutant mice.
丂Kondo Y, Tokuda N, Fan X, Yamashita T, Honke K, Takematsu H, Togayachi A, Ohta M, Kotzusumi Y, Narimatsu H,
丂Tajima O, Furukawa K, Furukawa K.
丂Biochem. Biophys. Res. Commun. 2009; 378:179-181 (IF: 2.548)

2) Unusual accumulation of sulfated glycosphingolipids in colon cancer cells.
丂Shida K, Misonou Y, Korekane H, Seki Y, Noura S, Ohue M, Honke K, Miyamoto Y.
丂Glycobiology 2009; 19:1018-1033 (IF: 3.929)

3) Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma.
丂Nakai E, Park K, Yawata T, Chihara T, Kumazawa A, Nakabayashi H, Shimizu K.
丂Cancer Invest. 2009 27:901-908 (IF: 2.105)

4) Dynamic modification of oral innervation during metamorphosis in Branchiostoma belcheri, the oriental lancelet.
丂Kaji T, Shimizu K, Artinger KB, Yasui K.
丂Biol Bull. 2009; 217:151-160 (IF: 1.942)

5) Blood kinetics of four intraperitoneally administered therapeutic candidate bacteriophages in healthy and
丂neutropenic mice.
丂Uchiyama J, Maeda Y, Takemura I, Chess-Williams R, Wakiguchi H, Matsuzaki S.
丂Microbiol Immunol. 2009 53:301-304 (IF: 1.562)

6) Morphological and genetic analysis of three bacteriophages of Serratia marcescens isolated from environmental
丂water.
丂Matsushita K, Uchiyama J, Kato S, Ujihara T, Hoshiba H, Sugihara S, Muraoka A, Wakiguchi H, Matsuzaki S.
丂FEMS Microbiol Lett. 2009 291:201-208 (IF: 2.199)

7) Characteristics of a novel Pseudomonas aeruginosa bacteriophage, PAJU2, which is genetically related to
丂bacteriophage D3.
丂Uchiyama J, Rashel M, Matsumoto T, Sumiyama Y, Wakiguchi H, Matsuzaki S.
丂Virus Res. 2009 139:131-134 (IF: 2.563)

8) Phase I study of a new radiosensitizer containing hydrogen peroxide and sodium hyaluronate for topical tumor
丂injection: A new enzyme-targeting radiosensitization treatment. Kochi Oxydol-Radiation Therapy for Unresectable
丂Carcinomas, Type II (KORTUC II).
丂Ogawa Y, Kubota K, Ue H, Kataoka Y, Tadokoro M, Miyakate K, Tsuzuki K, Yamanishi T, Itoh S, Hitomi J, Hamada N,
丂Kariya S, Fukumoto M, Nishioka A, Inomata T.
丂Int J Oncol 2009; 34: 609-618 (IF: 2.447)

9) Combination treatment of hydrogen peroxide and x-rays induces apoptosis in human prostate cancer PC-3 cells.
丂Kariya S, Sawada K, Kobayashi T, Karashima T, Shuin T, Nishioka A, Ogawa Y.
丂Int J Radiat Oncol Biol Phys 2009; 75: 449-454 (IF: 4.592)

挊彂

1) Honke K, Taniguchi N
丂Animal models to delineate glycan functionality. in 乬The Sugar Code. Fundamentals of Glycosciences (ed. Gabius
丂H-J)乭, pp.385-401, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2009

2) 惗嵶朎枌忋偺暘巕娫憡屳嶌梡傪娙曋偵夝愅偡傞
丂彫扟揟峅丄杮壠岶堦
丂抈敀幙丒妀巁丒峺慺 54(1): 65-71, 2009

3) 摐嵔偲晄擠徢
丂汭徏椦丄杮壠岶堦
丂惗懱偺壢妛61(2): 117-121, 2010

4) 崅楊幰揮堏惈擼庮釃偵懳偡傞摉嫵幒偺帋傒
丂愳惣桾丆栰拞戝怢丆拞嫃塱堦丆堜愳捈庽丆拞椦攷摴丆揷懞夒堦丆杙孾彶丆惔悈湪巌
丂Geriatric Neurosurgery 21:159-165, 擔杮榁擭擼恄宱奜壢尋媶夛帠柋嬊丄搶嫗丄2009擭

丂摿嫋戞4475469崋丂
丂俫俴俙寢崌惈儁僾僠僪丄偦傟傪僐乕僪偡傞俢俶俙抐曅偍傛傃慻傒姺偊儀僋僞乕
丂媨愳抭栫丄塅崅宐巕丂暯惉22擭3寧19擔

弌婅

丂摿婅2009-95888
丂庮釃摿堎揑僾儘儌乕僞乕偍傛傃偦偺梡搑
丂敪柧幰丗惔悈湪巌丄敧敠弐抝
丂弌婅擔丗暯惉21擭4寧10擔

曬摴

徏嶈栁揟

1) Nature News 2009.03.02 http://www.nature.com/news/2009/090302/full/news.2009.131.html
丂僼傽乕僕椕朄偵娭偡傞僐儊儞僩

2) BTJ乮擔宱BP幮僶僀僆僥僋僲儘僕乕僕儍僷儞乯傾僇僨儈僢僋2009.04.27
丂http://biotech.nikkeibp.co.jp/senmonn/btj_aca.jsp?jreq=btjnews&newsid=SPC2009042764114
丂戞83夞擔杮姶愼徢妛夛憤夛乮搶嫗丄2009.04.23-24乯偱偺敪昞撪梕乮僼傽乕僕梟嬠峺慺偵娭偡傞乯偺徯夘

彫愳嫳峅

1) TBS僥儗價丂忣曬摿僟僱丂2010擭1寧20擔

2) 枅擔怴暦挬姧丂巐崙斉丂2009擭7寧31擔
丂乽擕偑傫丂愗傜偢偵帯偟偨偄丂曻幩慄偺岠偒栚100%偵乿

3) 枅擔怴暦挬姧丂崅抦斉丂2009擭8寧23擔
丂乽偑傫忔傝墇偊偨彫愢壠丂摗尨旉嵐巕偝傫乿

1) Effect of intensive insulin therapy using a closed-loop glycemic control system in hepatic resection patients: a
丂prospective randomized clinical trial.
丂Okabayashi T, Nishimori I, Maeda H, Yamashita K, Yatabe T, Hanazaki K.
丂Diabetes Care. 2009; 32: 1425-1427 (IF: 6.718)

2) Perioperative insulin therapy using a closed-loop artificial endocrine pancreas after hepatic resection.
丂Okabayashi T, Maeda H, Sun ZL, Montgomery RA, Nishimori I, Hanazaki K.
丂World J Gastroenterol. 2009; 15: 4116-4121 (IF: 2.092)

3) Relationship between perioperative glycemic control and postoperative infections.
丂Hanazaki K, Maeda H, Okabayashi T.
丂World J Gastroenterol. 2009; 15: 4122-4125 (IF 2.092)

4) Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in
丂GR-deficient BE(2)C and T84 cells in vitro.
丂Tsugita M, Iwasaki Y, Nishiyama M, Taguchi T, Shinahara M, Taniguchi Y, Kambayashi M, Nishiyama A,
丂Gomez-Sanchez CE, Terada Y, Hashimoto K.
丂Mol Cell Endocrinol. 2009; 302: 18-25 (IF: 3.503)

5) Insulin exhibits short-term anti-inflammatory but long-term proinflammatory effects in vitro.
丂Iwasaki Y, Nishiyama M, Taguchi T, Asai M, Yoshida M, Kambayashi M, Terada Y, Hashimoto K.
丂Mol Cell Endocrinol. 2009; 298: 25-32 (IF: 3.503)

6) Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic
丂mice, an animal model of Cushing syndrome.
丂Shinahara M, Nishiyama M, Iwasaki Y, Nakayama S, Noguchi T, Kambayashi M, Okada Y, Tuda M, Stenzel-Poore MP,
丂Hashimoto K, Terada Y.
丂Endocr J. 2009; 56: 879-886 (IF: 1.806)

7) Hormonal regulation of glycolytic enzyme gene and pyruvate dehydrogenase kinase/phosphatase gene transcription.
丂Wang Z, Iwasaki Y, Zhao LF, Nishiyama M, Taguchi T, Tsugita M, Kambayashi M, Hashimoto K, Terada Y.
丂Endocr J. 2009; 56: 1019-1030 (IF: 1.806)

8) Pitavastation induces PON1 expression through P44/42 mitogen-activated protein kinase signaling cascade in Huh7
丂cells.
丂Arii 俲丆Suehiro T丆Ikeda Y丆Kumon Y丆Osaki F丆Inoue M丆Inada S丆Ogami N丆Takada H丆Hashimoto K丆Terada Y.
丂Atherosclerosis 2009; 202: 439-445

9) Visceral obesity is associated with the metabolic syndrome and elevated plasma retinol binding protein-4 level in
丂obstructive sleep apnea syndrome.
丂Makino S丆Fujiwara M丆Suzukawa K丆Handa H丆Fujie 俿丆Ohtaka 倄丆Komatsu Y丆Aoki Y丆Maruyama H丆Terada Y丆
丂Hashimoto K丆Sugimoto T
丂Horm Metab Res. 2009; 41: 221-226 (IF: 2.686)

10) Effects of angiotensin II type 1 receptor blocker on albumin-induced cell damage in human renal proximal tubular
丂epithelial cells.
丂Takao T丆Horino T丆Kagawa T丆Matsumoto R丆Inoue K丆Taguchi T丆Morita T丆Iwasaki Y丆Hashimoto K丆Terada Y.
丂Am J Nephrol. 2009; 29: 102-108 (IF: 3.481)

11) Effect of sevelamer hydrochloride on bone in experimental uremic rats.
丂Kuwahara M丆Inoshita S丆Terada Y, Sasaki S.
丂Therap Apher Dialysis. 2009; 13: 42-48 (IF: 1.140)

1) 杧栰懢榊丄 帥揷揟惗
丂揹夝幙堎忢. 崅丒掅Na寣徢丄 崅丒掅Cl寣徢. 愱栧堛偺偨傔偺恡憻昦妛丂戞2斉丂p115-121丄 撪嶳丂惞丄 晉栰峃擔屓丄 崱堜桾堦
丂曇.丂堛妛彂堾 2009.

2) 杧栰懢榊丄 帥揷揟惗
丂揹夝幙堎忢. 崅僫僩儕僂儉寣徢. 桝塼椕朄僷乕僼僃僋僩.p105-109, 斞栰桋旻曇. 梤搚幮 2009

3) 崄愳丂嫓丄 帥揷揟惗
丂Bartter徢岓孮. 撪暘斿戙幱愱栧堛僈僀僪僽僢僋.丂Pp236-238丄 惉悾岝塰丄暯揷寢婌弿丄搰捗復曇. 恌抐偲帯椕幮 2009

4) 惣嶳丂廩
丂撪壢妛憤榑丄椪彴徢忬乮敽 怣懢楴丆嶳杮榓棙曇乯旍枮丄傗偣丏撪壢妛彂 夵掶戞7斉 (vol.1)丗p294-296丄拞嶳彂揦丄搶嫗
丂2009

1) Estimation algorithm of butyrylcholinesterase for cirrhosis using neural network. IC-MED.
丂Hatakeyama Y, Kataoka H, Nakajima N, Watabe T, Okuhara Y.
丂IC-MED. 2009; 3: 77-86

2) Recurrent familial hypobetalipoproteinemia-induced nonalcoholic fatty liver disease after living donor liver
丂transplantation.
丂Harada N, Soejima Y, Taketomi A, Yoshizumi T, Uchiyama H, Ikegami T, Saibara T, Nishizaki T, Maehara Y.
丂Liver Transpl. 2009; 15: 806-809 (IF: 3.724)

1) 惣尨棙帯
丂C宆娞墛偺儀僗僩帯椕 (慘扟姴抝丄敧嫶峅丄幠揷幚曇) 帀朾娞 110-111暸丄堛妛彂堾丄搶嫗丄2009

2) 惣尨棙帯
丂2009 崱擔偺帯椕巜恓 (嶳岥揙丄杒尨岝晇丄暉堜師栴曇) NAFLD 401-402暸丄堛妛彂堾丄搶嫗丄2009

3) 惣尨棙帯
丂Annual Review 徚壔婍 2009 (椦婭晇丄擔斾婭暥丄忋惣婭晇丄壓悾愳揙曇) 旕傾儖僐乕儖惈帀朾娞墛偺椪彴偺恑揥, 157-166暸
丂拞奜堛妛幮丄搶嫗丄2009

4) 惣尨棙帯
丂徚壔婍幘姵 嵟怴偺帯椕 (悰栰寬懢榊丄忋惣婭晇丄堜夢摴晇曇) NAFLD 310-312暸丄撿峕摪丄搶嫗丄2009

5) 惣尨棙帯丄彫栰惓暥
丂昦婥偲栻僷乕僼僃僋僩BOOK 2009 (墶揷愮捗巕丄抮揷塅堦丄戝墇嫵晇娔廋) NASH(旕傾儖僐乕儖惈帀朾娞墛)丄 384-386暸
丂撿嶳摪丄搶嫗丄2009

6) 惣尨棙帯
丂栻偺慖傃曽丒巊偄曽偺僄僢僙儞僗丂乮塉怷惓梞丄戝惗掕媊娔廋乯NAFLD丒NASH丄 977-979暸丄撿嶳摪丄搶嫗丄2009

7) 惣尨棙帯丄戝惣嶰楴
丂娞憻昦恌椕Q&A丂乮壨揷弮抝丄嵅乆栘桾曇乯帺屓柶塽惈娞幘姵偺幚懺偼偳偆曄壔偟偰偄傞偐丠 17-18暸丄拞奜堛妛幮丄搶嫗
丂2009

8) 惣尨棙帯丄彫栰惓暥
丂娞憻昦恌椕Q&A丂乮壨揷弮抝丄嵅乆栘桾曇乯NASH偺帯椕偼偳偙傑偱恑曕偟偰偄傞偺偐丠 231-233暸丄拞奜堛妛幮丄搶嫗丄2009

9) 彫妢尨岝惉丄彫栰惓暥丄淎悾嫕丄栰嶈桋巕丄崅嫶徆栫丄娾嶈怣擇丄惣尨棙帯丄戝惣嶰楴
丂巁壔僗僩儗僗偲娞幘姵 (扟愳媣堦曇) 杊晽捠惞嶶搳梌偵傛傞旕傾儖僐乕儖惈帀朾惈娞忈奞(NAFLD)帯椕偺桳梡惈偍傛傃嶌梡婡彉偺
丂夝柧丄 133-137暸丄 傾乕僋儊僨傿傾幮丄 搶嫗丄 2009

1) B-type natriuretic peptide is predictive of hospitalization in community-dwelling elderly without heart diseases.
丂Shimizu Y, Nishinaga M, Takata J, Miyano I, Okumiya K, Matsubayashi K, Ozawa T, Yasuda N, Doi Y.
丂Geriatr Gerontol Int. 2009; 9: 148-154 (IF: 0.717)

2) Performance of integrated FDG-PET/contrast-enhanced CT in the diagnosis of recurrent uterine cancer: comparison
丂with PET and enhanced CT.
丂Kitajima K, Murakami K, Yamasaki E, Domeki Y, Kaji Y, Morita S, Suganuma N, Sugimura K.
丂Eur J Nucl Med Mol Imaging. 2009; 36: 362-372 (IF: 4.531)

3) Reliability of the proposed international classification of high-resolution computed tomography for occupational and
丂environmental respiratory diseases.
丂Suganuma N, Kusaka Y, Hering KG, Vehmas T, Kraus T, Arakawa H, Parker JE, Kivisaari L, Letourneux M, Gevenois
丂PA, Tuengerthal S, Crane MD, Shida H, Akira M, Henry DA, Nakajima Y, Hiraga Y, Itoh H, Hosoda Y
丂J Occup Health. 2009; 51:210-222 (IF: 1.252)

4) Performance of integrated FDG PET/contrast-enhanced CT in the diagnosis of recurrent colorectal cancer:
丂Comparison with integrated FDG PET/non-contrast-enhanced CT and enhanced CT.
丂Kitajima K, Murakami K, Yamasaki E, Domeki Y, Tsubaki M, Sunagawa M, Kaji Y, Suganuma N, Sugimura K.
丂Eur J Nucl Med Mol Imaging. 2009; 36: 1388-1396 (IF: 4.531)

摿奐2009-214016乮P2009-214016A乯丄傾儗儖僊乕敪徢梊杊梡僼傿儖僞乕
拞懞 桾擵丄擔壓 岾懃丄悰徖 惉暥丄烴堜 崕擭丄峃 浌攡丄廐娵 崙峀丄峅揷 検僯丄愇捤 屽巎丄塱堜 攷槦丄堫奯 捈庽丄揷拞 岹岾丄
抾擵撪 徛丄忋嶃 栁幚丄 暯惉21擭9寧24擔

1) Faster and stronger vascular "Biotube" graft fabrication in vivo using a novel nicotine-containing mold.
丂Sakai O, Kanda K, Takamizawa K, Sato T, Yaku H, Nakayama Y.
丂J Biomed Mater Res B Appl Biomater. 2009; 90:412-420 (IF: 2.185)

2) Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device
丂camera system: an advanced device for simultaneous capturing of color and near-infrared images during coronary
丂artery bypass graft.
丂Handa T, Katare RG, Sasaguri S, Sato T.
丂Interact Cardiovasc Thorac Surg. 2009; 9:150-154

3) Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal
丂efferent effects in sparsely innervated ventricular myocardium.
丂Kakinuma Y, Akiyama T, Sato T.
丂FEBS J. 2009; 276:5111-5125 (IF: 3.042)

4) Anti-Alzheimer's drug, donepezil, markedly improves long-term survival after chronic heart failure in mice.
丂Handa T, Katare RG, Kakinuma Y, Arikawa M, Ando M, Sasaguri S, Yamasaki F, Sato T.
丂J Card Fail. 2009; 15:805-811 (IF: 3.254)

弌婅

1) PCT/JP2009/066770
丂嶣憸憰抲丄嶣憸憰抲偺惂屼曽朄偍傛傃嶣憸憰抲偺惂屼僾儘僌儔儉
丂敪柧幰:嵅摗棽岾丄彫搱悢柧
丂弌婅擔:2009.9.28

2) PCT/JP2009/067352
丂奐岥峣傝
丂敪柧幰:嶳栰巌楴丄嵅摗棽岾
丂弌婅擔:2009.10.5

岞奐島墘

嵅摗棽岾

1) 恎懱揑丒惛恄揑偵晧扴偺彮側偄庤弍偺幚尰偵岦偗偰乣崅抦偐傜敪怣両悽奅弶偺夋婜揑側庤弍僫價僎乕僔儑儞僔僗僥儉乣
丂崅抦敪偑傫帯椕僼僅乕儔儉2010乣抧堟峷專傪傔偞偡丂偑傫帯椕尋媶偺嵟慜慄乣 2010.02.11. 崅怴RKC儂乕儖丄 崅抦巗